The flavonoid baicalin exhibits anti-inflammatory activity by binding to chemokines. View abstract. Phytother.Res 2007;21(9):900-903. Recently, researchers have paid more attention to its good therapeutic effect on UC. View abstract. Li, T., Li, N., Guo, Q., Ji, H., Zhao, D., Xie, S., Li, X., Qiu, Z., Han, D., Chen, X., and You, Q. Inhibitory effects of wogonin on catalytic activity of cytochrome P450 enzyme in human liver microsomes. View abstract. View abstract. A combination of Chinese herbs in use for more than 1,800 years reduced the gastrointestinal side effects of chemotherapy in mice, while actually enhancing the effects of the cancer treatment, Yale University researchers report. Hu, J. Shurygin, A. Y., Bezzubov, N. V., Ignatova, E. A., Nikolaev, S. M., and Viktorov, I. V. Baikal skullcap extract stimulates neurite growth in cultures of rat dorsal root Ganglia. Some medications are changed and broken down by the liver. Vestn.Ross.Akad.Med Nauk 1995;(1):29-38. In the summer, small, blue flowers present themselves as a shape that resembles a helmet or cap. It’s a slender plant with many branches reaching two to four feet in height. Huang Qin Tang (or PHY 906) is an 1800 year old herbal mixture used in Chinese medicine for the treatment of diarrhea, nausea, and vomiting. 2004;50(3):279-285. View abstract. Ceska.Slov.Farm. A., Ruscetti, F. W., and Wang, J. M. Flavonoid baicalin inhibits HIV-1 infection at the level of viral entry. 2008;8(3):264-268. At this time there is not enough scientific information to determine an appropriate range of doses for Baikal skullcap. Li, B. Q., Fu, T., Dongyan, Y., Mikovits, J. View abstract. Liu, G., Rajesh, N., Wang, X., Zhang, M., Wu, Q., Li, S., Chen, B., and Yao, S. Identification of flavonoids in the stems and leaves of Scutellaria baicalensis Georgi. Discontinue use immediately if you experience unexpected side effects. Do Not Take If You are taking warfarin or other blood thinners : Laboratory studies suggest Chinese skullcap has similar effects and … Z., Qin, B. W., Cheng, J. J., and Miao, H. Effect of Scutellaria flavonoids on KCN-induced damages in rat pheochromocytoma PC12 cells. Yotsumoto, H., Yanagita, T., Yamamoto, K., Ogawa, Y., Cha, J. Y., and Mori, Y. Inhibitory effects of oren-gedoku-to and its components on cholesteryl ester synthesis in cultured human hepatocyte HepG2 cells: evidence from the cultured HepG2 cells and in vitro assay of ACAT. See additional information. Planta Med 2011;77(5):455-460. The mixture, known in China as huang qin tang, has been shown in early trials to be effective at reducing some side effects of chemotherapy, including diarrhea, nausea and vomiting. Tong, R., Mehendale, S. R., Wang, C. Z., Shao, Z., and Yuan, C. S. Comparison of antioxidant effects of various Scutellaria baicalensis fractions and the potential role of catalase upregulation. Other names: Huang qin, Scutellariae radix, Chinese skullcap. Baikal skullcap might slow blood clotting. View abstract. Clin Pharmacol Ther 2007;83:471-6. It might cause drowsiness. Zhongguo Zhong.Yao Za Zhi 2008;33(9):1064-1066. J Nat Prod 1998;61:1413-5. Mu, R., Qi, Q., Gu, H., Wang, J., Yang, Y., Rong, J., Liu, W., Lu, N., You, Q., and Guo, Q. Ye, F., Xui, L., Yi, J., Zhang, W., and Zhang, D. Y. Anticancer activity of Scutellaria baicalensis and its potential mechanism. J Agric Food Chem 1-12-2005;53(1):8-16. View abstract. Other names: Huang qin, Scutellariae radix, Chinese skullcap. This is not a complete list of side effects and others may occur. View abstract. Armstrong, T. S. and Gilbert, M. R. Use of complementary and alternative medical therapy by patients with primary brain tumors. Skullcap, which is named due to its shape resembling that of a medieval helmet, is of the mint family, Lamiaceae, and ranges from blue to pink in color. View abstract. View abstract. 2009;110(4):1276-1287. 4-26-2011;135(1):179-185. Neurosci Lett. View abstract. Antitumor effects of Scutellariae radix and its components baicalein, baicalin, and wogonin on bladder cancer cell lines. Razina, T. G., Zueva, E. P., Litvinenko, V. I., and Kovalev, I. P. [A semisynthetic flavonoid from the Baikal skullcap (Scutellaria baicalensis) as an agent to enhance the efficacy of chemotherapy in experimental tumors]. Talk with your healthcare provider before using this product if you are taking lithium. 2nd ed. Cancer Lett. Chemotherapy causes a number of toxic side effects, which are usually treated with several different drugs with mixed success. Lu, H. F., Hsueh, S. C., Ho, Y. T., Kao, M. C., Yang, J. S., Chiu, T. H., Huamg, S. Y., Lin, C. C., and Chung, J. G. ROS mediates baicalin-induced apoptosis in human promyelocytic leukemia HL-60 cells through the expression of the Gadd153 and mitochondrial-dependent pathway. Arch Dis Child 1993;68:468-71. 2008;57(3):111-114. Baikal skullcap might have some of the same effects as estrogen. 12-10-2008;8(12):1652-1657. Kowalczyk, E., Krzesinski, P., Kura, M., Niedworok, J., Kowalski, J., and Blaszczyk, J. 2011;31(4):1130-1132. Botanical Name: Scutellaria baicalensis. [Pharmacological effects of flavonoids from Scutellaria baicalensis]. View abstract. Lee, S. W., Song, G. S., Kwon, C. H., and Kim, Y. K. Beneficial effect of flavonoid baicalein in cisplatin-induced cell death of human glioma cells. View abstract. Therefore, better alternative therapies for AD with minimal side effects … Daugel'-Dauge, N. O., Durnev, A. D., Kulakova, A. V., Seredenin, S. B., and Velichkovskii, B. T. [Corpuscular mutagenesis and its prevention]. Scutellaria baicalensis, better known as Chinese skullcap, is a flowering herb of the Labiatae family. Smol'ianinov ES, Gol'dberg VE, Matiash MG, et al. Rehmanniae : Sheng Di Huang + 3g Rx. Yang, X., Huang, S., Chen, J., Song, N., Wang, L., Zhang, Z., Deng, G., Zheng, H., Zhu, X. Q., and Lu, F. Evaluation of the adjuvant properties of Astragalus membranaceus and Scutellaria baicalensis GEORGI in the immune protection induced by UV-attenuated Toxoplasma gondii in mouse models. No patients in this study showed progression of prostate cancer up to 74 weeks after treatment commenced. Lin, C. C., Kuo, C. L., Lee, M. H., Lai, K. C., Lin, J. P., Yang, J. S., Yu, C. S., Lu, C. C., Chiang, J. H., Chueh, F. S., and Chung, J. G. Wogonin triggers apoptosis in human osteosarcoma U-2 OS cells through the endoplasmic reticulum stress, mitochondrial dysfunction and caspase-3-dependent signaling pathways. [Study of Scutellaria baicalensis and Baicalin against antimicrobial susceptibility of Helicobacter pylori strains in vitro]. Chinese journal of modern developments in traditional medicine 1990;10(5):278-9. Eur J Haematol. Ceska.Slov.Farm. With Gui Ban, controls Kidney Fire. 91 Unfortunately, the supplement also resulted in hormone-related adverse effects including nausea, impotence, breast tenderness, fluid retention, skin rash, blood clots, and pulmonary embolus. Whether co-administration of garlic has negative influence on Scutellaria baicalensis Georgi in treating models rats with pelvic inflammation? Cancer Lett. 2006;5(1):9-29. Wei, L., Lu, N., Dai, Q., Rong, J., Chen, Y., Li, Z., You, Q., and Guo, Q. Induction of apoptosis in prostate cancer cell lines by a flavonoid, baicalin. View abstract. Stop using Baikal skullcap at least 2 weeks before a scheduled surgery. Hu zhang is the Chinese name given to a plant with the scientific name of Polygonum cuspidatum. J Agric Food Chem 4-23-2008;56(8):2838-2845. J Ethnopharmacol. Toxicol.Appl.Pharmacol 8-1-2011;254(3):221-228. Ikemoto S, Sugimura K, Yoshida N, et al. View abstract. Kimura, Y., Okuda, H., and Ogita, Z. 1997;52(11-12):817-823. J Dermatol Sci 2007;46(1):31-40. Lee, E., Enomoto, R., Suzuki, C., Ohno, M., Ohashi, T., Miyauchi, A., Tanimoto, E., Maeda, K., Hirano, H., Yokoi, T., and Sugahara, C. Wogonin, a plant flavone, potentiates etoposide-induced apoptosis in cancer cells. View abstract. View abstract. Morgan SL, Baggott JE, Morel, L, Desmond R, and Kendrach AC. Zhang, X. W., Li, W. F., Li, W. W., Ren, K. H., Fan, C. M., Chen, Y. Y., and Shen, Y. L. Protective effects of the aqueous extract of Scutellaria baicalensis against acrolein-induced oxidative stress in cultured human umbilical vein endothelial cells. Zhong.Yao Cai. Urology. Discontinue use immediately if you experience unexpected side effects. Tsao, T. F., Newman, M. G., Kwok, Y. Y., and Horikoshi, A. K. Effect of Chinese and western antimicrobial agents on selected oral bacteria. This is not a complete list of side effects and others may occur. View abstract. Differential interaction of 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors with ABCB1, ABCC2, and OATP1B1. Planta Med 2001;67(5):396-399. Treatment of acute bronchiolitis with Chinese herbs. Nausea and vomiting are distressing symptoms for patients receiving chemotherapy. Am J Chin Med 2006;34(2):245-261. Medications that cause sleepiness are called sedatives. Baumann, S., Fas, S. C., Giaisi, M., Muller, W. W., Merling, A., Gulow, K., Edler, L., Krammer, P. H., and Li-Weber, M. Wogonin preferentially kills malignant lymphocytes and suppresses T-cell tumor growth by inducing PLCgamma1- and Ca2+-dependent apoptosis. Suppressive effect of wogonin on mite antigen-induced TARC expression. View abstract. Biol Pharm Bull 2003;26(1):79-83. The mixture, known in China as huang qin tang, has been shown in early trials to be effective at reducing some side effects of chemotherapy, including diarrhea, nausea and vomiting. Chan, E., Liu, X. X., Guo, D. J., Kwan, Y. W., Leung, G. P., Lee, S. M., and Chan, S. W. 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